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Exploring Sex Effects in Rehabilitation Medicine
Recent trials support the therapeutic utility of rTMS where a hyperexcitable unlesioned motor cortex can be targeted with slow frequency stimulation.
星空传媒视频 Project

Computational and Mathematical Modeling of Human Knee Joints
Anterior cruciate ligament (ACL) reconstructive surgeries, employing a total of 48 models, were conducted by virtually removing the ACL and then modeling the surgical preparation, tunnel architecture, graft pre-tensioning and fixation angle of a bone-patellar-tendon-bone autograft.
星空传媒视频 Project

Untangling of Lower Limb Synergies Post Stroke
Growing evidence demonstrates unique synergistic signatures in the lower limb (LL) post-stroke, with specific across-plane and across-joint representations. While the inhibitory role of the ipsilateral hemisphere in the upper limb (UL) has been widely reported, examination of the contralesional hemisphere (CON-H) in modulating LL expressions of synergies following stroke is lacking.
星空传媒视频 Project

Tracking spasticity in acute stroke
The proposed experiments use well-defined protocols with minimal risk from chronic stroke survivor research to test the monosynaptic reflex and TVR responses. We also gather clinical data in the acute and chronic stroke survivors.
星空传媒视频 Project

Evaluating the Use of Acute Intermittent Hypoxia to Improve Symptoms in Persons with Multiple Sclerosis
This pilot study (akin to our SCI pilot) evaluates if AIH will augment motor function in the lower limbs of PwMS.
星空传媒视频 Project

HANDS: A Multi-Center Clinical Trial to Evaluate the Effectiveness of Intermittent Hypoxia Therapy in Individuals with Spinal Cord Injury
This study investigates the effectiveness of daily acute intermittent hypoxia therapy (dAIH), coupled with a massed practice intervention or the use of high repetition training with the Rapael Glove, to improve upper-extremity function in individuals with chronic incomplete cervical SCI.
星空传媒视频 Project

Characterization of serum biomarkers in individuals with SCI receiving Acute Intermittent Hypoxia
We seek to quantify the serum inflammatory markers in individuals with SCI, and correlate inflammation with responsiveness to AIH therapy.
星空传媒视频 Project
The effect of botox on the hyperexcitability of the stretch reflex in spasticity
The objective of this study is to measure the electrical activity of single muscle fibers and to determine how this electrical activity changes after botulinum toxin injections.
星空传媒视频 Project

Tiny Machine Poised to Unlock Brain’s Mysteries
A team of scientists, led by researchers at Shirley Ryan 星空传媒视频, Northwestern University and the University of Illinois at Chicago, has developed novel technology promising to increase understanding of how brains develop, and offer answers on repairing brains in the wake of neurotrauma and neurodegenerative diseases.
星空传媒视频 Project

Preventing Nerve Injuries Acquired in the ICU by Patients with Severe COVID
A new study published in the October 2022 issue of the Journal of NeuroEngineering and Rehabilitation from a research team led by SRAlab clinicians identified the cause of — and hope for a potential prevention of — nerve injuries in patients treated in the intensive care unit for severe COVID-19.
星空传媒视频 Project

Reconstructive Surgery for People with Spinal Cord Injury
The Journal of Neurophysiology recently published a review by Adenike Adewuyi, MD PhD — a 2022 graduate of Shirley Ryan 星空传媒视频’s physical medicine and rehabilitation (PM&R) residency program — and her mentor, Colin Franz, MD, PhD, physician-scientist, at Shirley Ryan 星空传媒视频. The review defines a clinical framework for evaluating patients with spinal cord injuries to determine their candidacy for nerve transfer surgery.
星空传媒视频 Project

COMPLETE: Power Forward Study: A Cross-Sector, Multisite Clinical Trial of a Powered Knee-Ankle-Foot Orthosis
The overall objective of this study is to evaluate the impact of using the Nomad P-KAFO in people who have had a musculoskeletal or neurological injury that has affected their ability to walk.
星空传媒视频 Project